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Evidence-Based Evaluation of Preoperative vs Postoperative Use of Low-Molecular-Weight Heparin in Preventing Deep Vein Thrombosis in Elective Hip Surgery
Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.
The recent report by Hull et al1 describing the preoperativevs postoperative initiation of low-molecular-weight heparin(LMWH) prophylaxis in patients undergoing elective hip replacementprovides an excellent example of the clinical usefulness ofa meta-analysis. The number needed to treat (NNT) is a termthat is gaining importance in assessing therapy. It is definedas the number of patients needed to treat to achieve 1 favorableoutcome.2 The number needed to treat is calculated as l dividedby the absolute risk reduction and is a better measure of clinicalsignificance than relative risk reduction and statistical significance.3One other strength of NNT is that it can also be defined todescribe adverse effects of treatment (ie, number needed toharm [NNH]).
The following important question still needs to be addressed:would preoperative vs postoperative use of LMWH result in adecrease in the incidence of deep vein thrombosis (DVT) in . . . [Full Text of this Article]
