 |
|
Failure of Alcohol Reduction to Lower Blood Pressure in the PATHS Trial
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
The largely negative result of the Prevention and Treatment of Hypertension Study (PATHS)1 may be due to the fact that alcohol intake and blood pressure are not closely related at the levels of alcohol consumption observed. In 1987,2 we failed to detect an increase in systolic and diastolic blood pressure until male subjects (London Civil Servants) reported consuming 70 and 50 drinks of alcohol, respectively, per week (ethanol, 700 and 500 g/wk). In the PATHS trial, the average starting intake was reported as 440 g/wk. At this level, alcohol consumption may not be influencing blood pressure to a large extent; hence, the negative results.
It is possible that the relationship between lower levels of alcohol intake and blood pressure that is reported in many epidemiological studies is the result of gross underreporting of alcohol intake by the subjects. The resulting association of an increase in blood pressure with a (reported) . . . [Full Text of this Article]
RELATED ARTICLE
Prevention and Treatment of Hypertension Study (PATHS): Effects of an Alcohol Treatment Program on Blood Pressure
William C. Cushman, Jeffrey A. Cutler, Eleanor Hanna, Stephen F. Bingham, Dean Follmann, Thomas Harford, Patricia Dubbert, P. Scott Allender, Mary Dufour, Joseph F. Collins, Sandra M. Walsh, Gail F. Kirk, Matthew Burg, James V. Felicetta, Bruce P. Hamilton, Lois Anne Katz, H. Mitchell Perry, Jr, Mark L. Willenbring, Raj Lakshman, Robert J. Hamburger, and for the PATHS Group
Arch Intern Med. 1998;158(11):1197-1207.
ABSTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
The association between recipient alcohol dependency and long-term graft and recipient survival
Gueye et al.
Nephrol Dial Transplant 2007;22:891-898.
ABSTRACT
| FULL TEXT
|
