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In his review article about fibromyalgia syndrome (FM), Goldenberg¹ highlights the similarity between FM and chronic fatigue syndrome (CFS) and goes as far as stating that "these syndromes overlap so extensively that it may be concluded that each represents different presentations of the same general condition." This is unlikely to be the case because, as Crofford et al² pointed out, "comparison of hypothalamic-pituitary-adrenal axis function in FM with patients with CFS reveals differences despite the significant clinical overlap between these patients." Other recently observed differences, according to Evengard et al,³ "further support that FM and CFS are different disorders in spite of overlapping symptomatology."

Goldenberg¹ also states that the prognosis and outcome of FM and related conditions are adversely affected by inappropriate coping strategies and by catastrophic beliefs. He then claims that "cognitive-behavior therapy is a logical approach to change such beliefs and has been proved an effective tool in . . . [Full Text of this Article]