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Helicobacter pylori and Gastric Cancer: Both Primary and Secondary Preventive Measures Are Required
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We read with interest the article by Fendrik et al1 in the January issue of the ARCHIVES. The authors evaluated the cost-effectiveness of primary prevention of gastric cancer based on the eradication of the Helicobacter pylori infection in different epidemiological contexts and using different strategies. Both single H pylori serological testing and H pylori testing followed by confirmatory tests resulted in a positive cost-effective balance, proportional to the cancer risk associated with the considered population.
The article was concerned with the "Clinical and Economic Effects of Population-Based Helicobacter pylori Screening"; from the perspective of the clinician, however, we believe that evaluation of computer modeling might also have been considered. The disease burden on society associated with H pylori is immense, and one may ask whether assumptions used in the computer model were representative of the actual clinical problem.2-3 Computer models of complex questions are always challenged by the number of . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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The long term outcome of gastric non-invasive neoplasia
Rugge et al.
Gut 2003;52:1111-1116.
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