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Antihypertensives
Much Ado About Lipids
Arch Intern Med. 1999;159:535-537.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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THE QUESTION of what blood pressure medication to use in which patient remains one of great interest and concern; Lakshman et al1 in this issue of the ARCHIVES address 1 factor that some clinicians may use in guiding their antihypertensive medication decision: the effect of these medications on the lipid profile.
LIPIDS INFLUENCE CARDIOVASCULAR DISEASE
Lipids have repeatedly been shown to predict cardiovascular events; and lipid reduction, particularly with use of statins, has been shown to produce potent benefit to overall as well as cardiovascular mortality rates in middle-aged men with heart disease,2 and to benefit cardiovascular events in other groups.2-3 Even in those with "normal" lipids, lipid reduction using statins has led to outcome benefits in those at highest risk of cardiovascular disease4 (although statins may exert some of their benefit through nonlipid mechanisms5). For these reasons, interest attaches to effects of antihypertensives on lipids, particularly because patients with hypertension are at . . . [Full Text of this Article]
STUDY DOES NOT PRECLUDE A MEANINGFUL EFFECT ON LIPIDS
EFFECTS ON LIPIDS ARE SUBSIDIARY TO EFFECTS ON MORTALITY
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Antihypertensive Agents in Diabetic Patients: Great Benefits, Special Risks
Peters and Hsueh
Arch Intern Med 1999;159:541-542.
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