Calcium channel blockers are commonly used to treat systemic hypertension in patients with intracranial hypertension. We describe a 35-year-old woman whose benign intracranial hypertension worsened with amlodipine therapy.
Report of a Case.
This woman first presented with headaches and was found to have papilledema with no focal neurological deficit. A computed tomographic scan of the brain was normal. A lumbar puncture showed raised cerebrospinal fluid (CSF) pressure although the results of the CSF examination were normal. Benign intracranial hypertension was diagnosed and she was managed with repeated lumbar punctures.
She was given the diagnosis of hypertension 2 years later. Results of clinical examination were normal except for a persistently raised blood pressure of around 170/110 mm Hg. Serum electrolyte, creatinine, and urea levels were normal.
She was started on a regimen of amlodipine with good control of her blood pressure. However, her headache returned and fundal examination showed papilledema.
Lumbar puncture revealed a CSF . . . [Full Text of this Article]
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