This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on ISI (1)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The article by Cantalamessa and colleagues¹ points out that thyroid nodules occur with a high frequency in patients with Graves disease as determined by ultrasonography and pathological examination findings. Nevertheless, the authors discovered only 1 case of carcinoma among 315 consecutive patients (0.3%), including 106 with nodules. Surprisingly, this is a rather low frequency compared with previous studies and the findings from a recent series.² We assume that this low frequency is the result of the fact that only 20 patients underwent surgery.

In our experience, it is difficult to rule out the possibility of carcinoma with certainty without pathological examination.³ Near total thyroidectomy is still a popular definitive treatment for Graves disease in our country, with more patients undergoing surgery than are treated with radioiodine. In the past 4 years, 115 thyroidectomies were performed at our institution for patients with Graves disease. As summarized in Table 1, one . . . [Full Text of this Article]

RELATED ARTICLE

Thyroid Nodules in Graves Disease and the Risk of Thyroid Carcinoma
Luigi Cantalamessa, Marina Baldini, Alessandra Orsatti, Laura Meroni, Vincenzina Amodei, and Daniela Castagnone
Arch Intern Med. 1999;159(15):1705-1708.
ABSTRACT | FULL TEXT