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  Vol. 160 No. 14, July 24, 2000 TABLE OF CONTENTS
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Nonulcer Dyspepsia and Helicobacter pylori Infection

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The recent study by Greenberg and Cello1 reached negative conclusions regarding the opportunity to eradicate Helicobacter pylori in patients with nonulcer dyspepsia. The authors found that, at 1 year, the change in dyspeptic symptoms was the same in the group receiving an eradicating treatment as in the placebo group. Furthermore, patients with persistent H pylori infection showed a greater, but not significant, improvement in symptoms than those with successful eradication during the follow-up.

Literature data on the role of H pylori infection in nonulcer dyspepsia are somewhat controversial. Blum et al2 substantially confirmed the results of Greenberg and Cello. On the contrary, Jaakkimainen et al,3 reporting the results of a meta-analysis of 23 observational studies, recently found that for patients in whom H pylori was eradicated, dyspeptic symptoms were 90% more likely to improve compared with patients in whom the infection was not eliminated.

However, we have identified problems with . . . [Full Text of this Article]



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