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Pyoderma gangrenosum is a disorder that can be idiopathic or associated with several systemic conditions, the most frequent being inflammatory bowel disease (in particular ulcerative colitis), rheumatoid arthritis, paraproteinemia (mainly IgA), and hematologic neoplasias.^1-3 Pathergy is also commonly seen in patients with PG and usually presents because of a previous mild lesion, such as a needle puncture.² Pathergic reaction, which was observed as a skin lesion (pustule or papule) by Blobner⁴ in 1937, appears some hours after a puncture on the skin and is nonspecific. It has also been described in other conditions such as Behçet disease, rheumatoid arthritis, sarcoidosis, idiopathic erythema nodosum, and genital herpes.

Report of a Case

We report the case of a 48-year-old woman with a history of umbilical hernia surgery, spondyloarthritis, reactive depressive-anxiety syndrome, and voluntary drug intoxication. Two years earlier, she had several episodes of bloody diarrhea; the last episode occurred 6 months before with a 16-week evolution. . . . [Full Text of this Article]

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pyoderma gangrenosum in a syringe driver site of a patient with non-Hodgkin's lymphoma
Curtis and Douglas
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ABSTRACT