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  Vol. 160 No. 16, September 11, 2000 TABLE OF CONTENTS
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Loss of the Sense of Humor

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In mid-May, my 94-year-old father and I were discussing the significance of 0 and its impact on theoretical mathematics. Four weeks later, he was totally demented. He was taking no medication, and all routine blood and urine studies, brain imaging, and a spinal tap yielded no diagnosis. One week later, a high titer of Lyme antibody was found in a cerebrospinal fluid specimen, and the diagnosis of neuroborreliosis was unequivocally substantiated by Western blot analysis. Eight weeks after a 28-day course of intravenous ceftriaxone sodium (1 g/d), his mental function returned to an estimated 90% of his premorbid intellect. That was when I gave him a short vignette written in a humorous vein, relating to the purchase of a ballpoint pen.

I awaited his response with interest. To my disappointment, all he said was, "Where is the pen? May I see it?" I was disappointed, but replied "I'll get you . . . [Full Text of this Article]



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