 |
 |

Loss of the Sense of Humor
 |
 |
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
 |
 |
In mid-May, my 94-year-old father and I were discussing the significance of 0 and its impact on theoretical mathematics. Four weeks later, he was totally demented. He was taking no medication, and all routine blood and urine studies, brain imaging, and a spinal tap yielded no diagnosis. One week later, a high titer of Lyme antibody was found in a cerebrospinal fluid specimen, and the diagnosis of neuroborreliosis was unequivocally substantiated by Western blot analysis. Eight weeks after a 28-day course of intravenous ceftriaxone sodium (1 g/d), his mental function returned to an estimated 90% of his premorbid intellect. That was when I gave him a short vignette written in a humorous vein, relating to the purchase of a ballpoint pen.
I awaited his response with interest. To my disappointment, all he said was, "Where is the pen? May I see it?" I was disappointed, but replied "I'll get you . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
 |
Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects
Atkinson et al.
Am. J. Clin. Nutr. 2008;87:577-585.
ABSTRACT
| FULL TEXT
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women
Chiuve et al.
Am. J. Clin. Nutr. 2007;86:1073-1081.
ABSTRACT
| FULL TEXT
Modulation of the Homocysteine-Betaine Relationship by Methylenetetrahydrofolate Reductase 677 C->T Genotypes and B-Vitamin Status in a Large-Scale Epidemiological Study
Holm et al.
J. Clin. Endocrinol. Metab. 2007;92:1535-1541.
ABSTRACT
| FULL TEXT
Determination of Choline, Betaine, and Dimethylglycine in Plasma by a High-Throughput Method Based on Normal-Phase Chromatography-Tandem Mass Spectrometry
Holm et al.
Clin. Chem. 2003;49:286-294.
ABSTRACT
| FULL TEXT
Selenium Supplements Do Not Increase Plasma Total Homocysteine Concentrations in Men and Women
Venn et al.
J. Nutr. 2003;133:418-420.
ABSTRACT
| FULL TEXT
Homocysteine Determinants and the Evidence to What Extent Homocysteine Determines the Risk of Coronary Heart Disease
De Bree et al.
Pharmacol. Rev. 2002;54:599-618.
ABSTRACT
| FULL TEXT
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects
Schwab et al.
Am. J. Clin. Nutr. 2002;76:961-967.
ABSTRACT
| FULL TEXT
|