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Brucella melitensis is a Gram-negative bacillus that causes a zoonosis that is endemic in Spain. It can be asymptomatic, diagnosed only by positive serological test results, or symptomatic, leading to acute or chronic brucellosis. Chronic brucellosis may present in multiple forms, including osteomyelitis, arthritis, splenic abscess, genitourinary infections, neurological infection (neurobrucellosis), and endocarditis.¹ The last form is frequently associated with a poor outcome.¹

Infection is a serious complication after placement of permanent endocardial pacemakers. The rates of pacemaker infection have varied from 0.13% to 19.9% of the devices implanted.^2-3 Staphylococci (Staphylococcus epidermidis and Staphylococcus aureus), Enterobacteriaceae, Pseudomonas aeruginosa, and Streptococcus and Enterococcus species are the most common etiologic agents.^4-6 In a few patients who have been reported to develop bacteremic infection or endocarditis due to metastatic spread of bacteria, unusual microorganisms may be responsible. Among them, Brucella species have been even more infrequently associated with this infection.

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Report of a Case


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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pacemaker Infection Due to Brucella melitensis: A Case Report
Ulkar et al.
Arch Intern Med 2001;161:1910-1911.
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