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We have read the article "Homeopathy Re-revisited"¹ with interest and strongly disagree with the author's viewpoint that the homeopathic concept may be compatible with Western medical knowledge. To support his argument, Eskinazi maintains that the 2 basic principles of homeopathy, the law of similars and the claimed biological effect of very high (sub-Avogadro) dilutions, are not necessarily in conflict with current scientific observations. In homeopathic practice, however, the 2 different laws of similars are applied differently by homeopaths. The one put forward by Hahnemann² himself dictates that an illness can be cured by administering a drug that, in the same dose, would cause similar symptoms in healthy subjects (the curative effect depends on a difference in biological response between diseased and healthy subjects). Hahnemann, therefore, usually administered a single dose, in order to avoid having his patients becoming ill again as a result of the toxic effects of the medication. . . . [Full Text of this Article]