This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on ISI (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Restless legs syndrome has been emphasized as a potential adverse effect of selective serotonin reuptake inhibitors (SSRIs).¹ In the community, leg restlessness at bedtime occurs in more than 15% of adults and is more prevalent with increasing age and in women.² Noting a reduction in leg restlessness at night in some of our patients who were treated with SSRIs, we retrospectively reviewed the experience of 113 consecutive patients attending a hospital medical clinic who had been prescribed an SSRI. Questionnaires were returned by 66 patients aged 19 to 86 years. Women outnumbered men (43 vs 23), and all 66 patients began taking an SSRI (sertraline, n=29; paroxetine, n=34; or fluoxetine, n=3) 3 months to 3 years (median, 8 months) before our study.

Restless legs symptoms predating treatment with SSRIs were acknowledged by 65% of respondents (n=43) when prompted by the following description: " . . . typically occurs on going . . . [Full Text of this Article]