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Prostate Cancer Screening in High-Risk Patients
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Many forms of cancer, such as prostate, breast, and colon cancer, can run in families. Patients with afflicted relatives often request screening, and they look to us for guidance.
Report of a Case
A 72-year-old white man whose father died from prostate cancer had the following prostate-specific antigen (PSA) values: 1.2 ng/mL in December 1996, 1.4 ng/mL in July 1997, 1.6 ng/mL in May 1998, 1.6 ng/mL in October 1998, and 1.9 ng/mL in March 1999. At the patient's request, because of the rise in PSA levels, urological consultation was obtained, and adenocarcinoma of the prostate (Gleason score, 6) was subsequently diagnosed.
Comment
This case highlights the uncertainty surrounding prostate cancer screening, especially in high-risk patients. Should a lower cutoff value than 4.0 ng/mL be considered a red flag? Should we use PSA or PSA volume testing in this population? Should the rise in PSA levels be used, and if so, how much of an . . . [Full Text of this Article]
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