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Arch Intern Med. 2001;161:124.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In adult patients with the human immunodeficiency virus (HIV), lymphoid interstitial pneumonitis (LIP) is part of a diffuse CD8-infiltrative lymphocytosis syndrome.¹ Lung biopsy is the criterion-standard to diagnose LIP.² Lymphoid interstitial pneumonitis is characterized by a histologic pattern of diffuse infiltration with predominantly small lymphocytes and plasma cells in the alveolar septa and along the lymphatic vessels. In a recent study, gene rearrangement analysis of alveolar lymphocytes by polymerase chain reaction (PCR) seemed to be sensitive enough for the diagnosis of B-cell pulmonary non-Hodgkin lymphoma in immunocompetent patients.³

Patients with HIV are at high risk for the development of non-Hodgkin lymphoma characterized by an unusual extranodal involvement.⁴ Therefore, molecular biology techniques may be helpful in diagnosing lymphoid pulmonary infiltrates in patients with HIV.

Report of Cases

Case 1

A 39-year-old, nonsmoking, Haitian, heterosexual man was known to be HIV-seropositive since 1989. Four years later, he developed a worsening dyspnea and cough. A chest radiograph and . . . [Full Text of this Article]

Case 2

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