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Primary Cerebellar Degeneration and HIV
Arch Intern Med. 2001;161:1555-1556.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Cerebellar degeneration associated with human immunodeficiency (HIV)
infection in the absence of cognitive impairment is exceedingly rare. To date,
this association has been the subject of a few reports, representing mostly
anecdotal findings. A causative association has been postulated, although
significant debate continues over whether or not cerebellar degeneration is
actually a complication of HIV infection. We describe an HIV-positive patient
with subacute cerebellar syndrome in the absence of any cognitive impairment
or alternative cause of cerebellar degeneration.
Report of a Case
A 49-year-old African American homosexual man was diagnosed as having
HIV disease in 1994 during a hospitalization for Pneumocystis
carinii pneumonia and Molluscum contagiosum
infection. His exposure to HIV predated the death of his partner in 1991.
Serological tests revealed a CD4 cell count of 12/µL. The patient responded
immunologically to antiretroviral therapy, his CD4 count remaining in the
150 to 250/µL range during treatment, despite only moderate suppression
of his HIV . . . [Full Text of this Article] Comment
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Productive infection of cerebellar granule cell neurons by JC virus in an HIV+ individual
Du Pasquier et al.
Neurology 2003;61:775-782.
ABSTRACT
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