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What Is Proper Treatment for Wegener Granulomatosis?
Arch Intern Med. 2001;161:1777-1778.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Previously in the ARCHIVES, we reported a case of late recurring Wegener
granulomatosis (WG) that was successfully treated with combination therapy
consisting of cyclophosphamide and cyclosporin.1
The 36-year-old woman, whose WG recurred 18 years after her first remission
with cyclophosphamide and corticosteroid therapy, was treated with cyclosporin
and prednisolone after undergoing a resection of corneal granuloma. However,
because of severe tracheal stenosis with subglottic granuloma, cyclophosphamide
was added to her treatment regimen, and with the combination therapy of cyclophosphamide,
cyclosporin, and prednisolone, her condition improved rapidly. Cyclophosphamide
therapy was discontinued in January 2000 (8 months after the initiation),
because of the patient's clinical stability and her rejection of cyclophosphamide
therapy. In October 2000, she was referred to our clinic with hematuria, and
subsequent evaluation resulted in a diagnosis of urinary bladder cancer. The
patient underwent total cystectomy in February 2001. The treatment for this
refractory and clinical malignant disease is . . . [Full Text of this Article]Report of a Case
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