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  Vol. 161 No. 15, August 13, 2001 TABLE OF CONTENTS
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Evaluation of Patients With Chest Pain and Normal Coronary Angiograms

Leonard Schwartz, MD; Martial G. Bourassa, MD

Arch Intern Med. 2001;161:1825-1833.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Over 1 million coronary angiograms are performed in North America annually, and a significant number are interpreted as normal. In the Coronary Artery Surgery Study Registry of the 1970s, normal angiograms were found in 19% of patients,1 and the prevalence may not have changed in the current era of more sophisticated noninvasive testing. A recent study found that 19% of patients had no arteriographic evidence of disease.2 For women selected for angiography, a normal result is found 3 times more frequently than for men.1-2 Further elucidation of the diagnosis in a patient population of this size is of obvious importance. However, correctly investigating and managing the treatment for such patients can be challenging. On the one hand, a potentially serious, yet manageable condition must not be overlooked. On the other hand, excessive anxiety over a problem that may not exist or may not . . . [Full Text of this Article]

ARE THE CORONARY ANGIOGRAMS TRULY NORMAL?

Large-Vessel Coronary Vasospasm

Missed Coronary Artery Lesions

Diffuse Disease

Eccentric Plaques

Flush Occlusions

Vessel Foreshortening

Aorto-ostial Lesions

Branch Ostial Lesions

Overlapping Side Branches

Disease of the Left Main Coronary Artery

Congenital Coronary Anomalies

Myocardial Bridges

IS THERE A NONCORONARY CARDIAC CAUSE OF ISCHEMIC CHEST PAIN?

IS THERE A NONCARDIAC CAUSE OF CHEST PAIN?

The Distal Esophagus

Chest Pain of Musculoskeletal Origin

CHEST PAIN WITH A BROAD SPECTRUM OF POSTULATED MECHANISMS: SYNDROME X

Impaired Coronary Flow Reserve

Microvascular Spasm

Patchy Prearteriolar Vasoconstriction

Disease of the Small Arteries

Occult Large-Vessel Disease

Pain Due to Excessive Adenosine Effect Without Ischemia

Psychological Disorders

Hormonal Deficiency

Other Theories and Contributing Factors

Therapeutic Implications

CONCLUSIONS

From the University of Toronto and the Toronto General Hospital, University Health Network, Toronto, Ontario (Dr Schwartz), and the University of Montreal and Montreal Heart Institute, Montreal, Quebec (Dr Bourassa).



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Long-term survival of patients with chest pain syndrome and angiographically normal or near-normal coronary arteries: the additional prognostic value of dipyridamole echocardiography test (DET)
Sicari et al.
Eur Heart J 2005;26:2136-2141.
ABSTRACT | FULL TEXT  

Ischaemia and outcome with normal coronary arteries
Marwick
Eur Heart J 2005;26:2077-2078.
FULL TEXT  

Amelioration of Microvascular Angina with Arginine Supplementation
Schwartz
ANN INTERN MED 2003;138:160-160.
FULL TEXT  

Functional Chest Pain of Presumed Esophageal Origin
Ringel et al.
Arch Intern Med 2002;162:365-366.
FULL TEXT  





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