
Amelanotic Melanoma Presenting as a Scar
Arch Intern Med. 2001;161:1912-1913.
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Our review of the literature (MEDLINE searched 1966-March 2001) established
that amelanotic melanoma represents 1.8% to 8.1% of cutaneous malignant melanoma.1 Amelanotic melanoma often goes clinically undiagnosed
because of its wide range of clinical appearances and lack of pigmentation.
Little is known about the role of mechanical trauma in the pathogenesis of
melanoma. We have been unable to find references in the literature concerning
the occurrence of amelanotic melanoma in connection with scars but report
2 clinical cases of amelanotic melanoma that had developed on a posttraumatic
scar.
Report of Cases
Case 1
A 40-year-old white man presented with a small pink nodular lesion on
the palm of the hand. He had noticed the lesion a few weeks previously, and
it had gradually increased in size. Two months before this, he had received
a local trauma with superficial erosion when playing paddle tennis. Some weeks
later, because of discomfort and the lesion's failure to heal, . . . [Full Text of this Article] Case 2 Comment
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