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Arch Intern Med. 2001;161:1912-1913.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Our review of the literature (MEDLINE searched 1966-March 2001) established that amelanotic melanoma represents 1.8% to 8.1% of cutaneous malignant melanoma.¹ Amelanotic melanoma often goes clinically undiagnosed because of its wide range of clinical appearances and lack of pigmentation. Little is known about the role of mechanical trauma in the pathogenesis of melanoma. We have been unable to find references in the literature concerning the occurrence of amelanotic melanoma in connection with scars but report 2 clinical cases of amelanotic melanoma that had developed on a posttraumatic scar.

Report of Cases

Case 1

A 40-year-old white man presented with a small pink nodular lesion on the palm of the hand. He had noticed the lesion a few weeks previously, and it had gradually increased in size. Two months before this, he had received a local trauma with superficial erosion when playing paddle tennis. Some weeks later, because of discomfort and the lesion's failure to heal, . . . [Full Text of this Article]

Case 2

Comment

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