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Arch Intern Med. 2001;161:2259-2260.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Drug resistance may be the main cause of antiretroviral treatment failure in human immunodeficiency virus (HIV) infection. Drug-resistant mutations have been described for all 3 classes of antiretroviral drugs. The first case of sexual transmission of a multidrug-resistant variant (MDR) was published in 1998.¹ We report a new case.

Report of a Case

On November 14, 1998, a 24-year-old man was admitted for a prostate infection and an anal fistula. He had had unprotected receptive anal intercourse with a male partner 3 days earlier. The anal fistula was treated surgically, and therapy with ofloxacin was started. Pharyngitis and fever developed. A serologic assay for HIV was negative. Amoxicillin was added to his therapy regimen, and the patient was discharged on November 21, 1998. Two days later a maculopapular rash developed, prompting the substitution of ofloxacin and amoxicillin with co-trimoxazole (sulfamethoxazole and trimethoprim). Five days later diffuse urticaria occurred.

On December 6, 1998, he was . . . [Full Text of this Article]

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