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Preclinical Cushing Disease
Arch Intern Med. 2001;161:892-893.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Report of a Case
In March 1995, a 67-year-old woman came to the outpatient clinic because
her body weight had increased from 48 to 55 kg during 1 year. On physical
examination, she was neither cushingoid nor hypertensive. Her morning plasma
corticotropin level was 19 pmol/L (reference range, 1-12 pmol/L). One milligram
of dexamethasone completely suppressed plasma corticotropin and cortisol levels.
The corticotropin and cortisol values remained between 6 and 9 pmol/L and
323 and 400 nmol/L, respectively, after 3 years.
At this stage, the patient was referred to our endocrine clinic at Kochi
Medical School, Nankoku, Japan. A T1-weighted magnetic resonance image demonstrated
enlargement of the pituitary gland on the left side but did not identify a
definite pituitary adenoma. Plasma corticotropin, serum cortisol, and urinary
free cortisol values were within the normal range, but diurnal changes of
corticotropin and cortisol were not seen. Although the corticotropin level
was not completely suppressed, the . . . [Full Text of this Article] Comment
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Occult Cushing's Syndrome in Type-2 Diabetes
Catargi et al.
J. Clin. Endocrinol. Metab. 2003;88:5808-5813.
ABSTRACT
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