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  Vol. 161 No. 6, March 26, 2001 TABLE OF CONTENTS
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Preclinical Cushing Disease

Arch Intern Med. 2001;161:892-893.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Report of a Case

In March 1995, a 67-year-old woman came to the outpatient clinic because her body weight had increased from 48 to 55 kg during 1 year. On physical examination, she was neither cushingoid nor hypertensive. Her morning plasma corticotropin level was 19 pmol/L (reference range, 1-12 pmol/L). One milligram of dexamethasone completely suppressed plasma corticotropin and cortisol levels. The corticotropin and cortisol values remained between 6 and 9 pmol/L and 323 and 400 nmol/L, respectively, after 3 years.

At this stage, the patient was referred to our endocrine clinic at Kochi Medical School, Nankoku, Japan. A T1-weighted magnetic resonance image demonstrated enlargement of the pituitary gland on the left side but did not identify a definite pituitary adenoma. Plasma corticotropin, serum cortisol, and urinary free cortisol values were within the normal range, but diurnal changes of corticotropin and cortisol were not seen. Although the corticotropin level was not completely suppressed, the . . . [Full Text of this Article]


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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Occult Cushing's Syndrome in Type-2 Diabetes
Catargi et al.
J. Clin. Endocrinol. Metab. 2003;88:5808-5813.
ABSTRACT | FULL TEXT  





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