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Arch Intern Med. 2001;161:893.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Statins are highly effective in the treatment of hypercholesterolemia, an effect that is hampered by adverse reactions,¹ such as rhabdomyolysis, which may threaten a patient's life.² Newer statins, such as cerivastatin sodium, are administered in dosages that are much lower than the older statins, such as pravastatin sodium, lovastatin, or simvastatin. It is said that the reduced amount of active product leads to a lower incidence of adverse reactions and preserves the cholesterol-lowering effect³; as a result, no cases of rhabdomyolysis associated with cerivastatin therapy have been described.

Report of a Case

We report the case of a 77-year-old woman who was admitted to our hospital with progressive, painful weakness affecting her both lower and upper limbs; these symptoms began 15 days before admission, when therapy with cerivastatin sodium, 0.2 mg daily, was instituted, and worsened each day. The patient had non–insulin-dependent diabetes mellitus, hypertension, ischemic hypertensive myocardiopathy, and hyperlipidemia, which was previously . . . [Full Text of this Article]

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RELATED LETTERS

Other Reports of Cerivastatin-Induced Rhabdomyolysis
Michael Gabay and Amy Lodolce
Arch Intern Med. 2001;161(21):2629.
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Another Report of Acute Rhabdomyolysis Following Cerivastatin Monotherapy
Haralampos J. Milionis, Tania G. Tsapoga, Moses S. Elisaf, E. González-Reimers, F. Santolaria-Fernández, E. García-Valdecasas-Campelo, E. Rodríguez-Rodriguez, and A. López-Lirola
Arch Intern Med. 2001;161(21):2629-2630.
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Case Reports of Rhabdomyolysis Associated With Cerivastatin Therapy
Suzanne Simpson
Arch Intern Med. 2001;161(21):2630-2631.
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