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Pituitary Gangliocytoma-Adenoma Presenting With Acromegaly: Response to Treatment
Arch Intern Med. 2001;161:1010-1011.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Acromegaly is the clinical syndrome that results from excessive secretion
of growth hormone (GH). The most common cause of acromegaly is a somatotroph
(GH-secreting) adenoma of the anterior pituitary gland. In rare cases, overproduction
of GH-releasing hormone (GHRH) by functional hypothalamic tumors such as hamartomas
and gangliocytomas may cause acromegaly by inducing proliferation of GH-secreting
pituitary cells.1 However, to our knowledge,
few cases of combined pituitary adenoma and sellar gangliocytoma presenting
with acromegaly have been reported.2
We report a rare case of a woman with acromegaly produced by a sellar
mixed gangliocytoma-adenoma and the response to treatment 3 years after the
surgical approach.
Report of a Case
Findings of a computed tomographic (CT) scan incidentally revealed a
pituitary macrotumor in a 39-year-old woman after mild traumatic brain injury.
The CT scan showed an intrasellar lesion extending into the suprasellar region.
Magnetic resonance imaging (MRI) scans demonstrated a pituitary tumor measuring
2.5 x 2 x . . . [Full Text of this Article] Comment
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