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  Vol. 161 No. 7, April 9, 2001 TABLE OF CONTENTS
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Pituitary Gangliocytoma-Adenoma Presenting With Acromegaly: Response to Treatment

Arch Intern Med. 2001;161:1010-1011.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Acromegaly is the clinical syndrome that results from excessive secretion of growth hormone (GH). The most common cause of acromegaly is a somatotroph (GH-secreting) adenoma of the anterior pituitary gland. In rare cases, overproduction of GH-releasing hormone (GHRH) by functional hypothalamic tumors such as hamartomas and gangliocytomas may cause acromegaly by inducing proliferation of GH-secreting pituitary cells.1 However, to our knowledge, few cases of combined pituitary adenoma and sellar gangliocytoma presenting with acromegaly have been reported.2

We report a rare case of a woman with acromegaly produced by a sellar mixed gangliocytoma-adenoma and the response to treatment 3 years after the surgical approach.

Report of a Case

Findings of a computed tomographic (CT) scan incidentally revealed a pituitary macrotumor in a 39-year-old woman after mild traumatic brain injury. The CT scan showed an intrasellar lesion extending into the suprasellar region. Magnetic resonance imaging (MRI) scans demonstrated a pituitary tumor measuring 2.5 x 2 x . . . [Full Text of this Article]


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