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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Coronary heart disease is a major public health problem, and even a small reduction in the number of adverse events will go a long way toward reducing morbidity and mortality, thereby cutting down the cost of health care significantly. Minimum intensity anticoagulation therapy as a primary preventive measure is a promising area that has been examined by MacCallum et al¹ and has huge implications in terms of resource allocation.

However, as MacCallum et al¹ point out, some issues remain unresolved: (1) In this study, all the subjects were men, which is not representative of the population groups. If women might also benefit from this form of therapy, more research is needed on when (before or after menopause) women should begin treatment. (2) It is not clear how fast the subjects achieved target international normalized ratio or how closely they need to be monitored to ensure success. (3) The safety of . . . [Full Text of this Article]