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We read with interest the article by Ross et al¹ about the risk of personnel-to-patient transmission of hepatitis C virus (HCV) in which the authors presented model-based calculations for surgical settings. Being involved in the investigations of suspected personnel-to-patient transmissions of bloodborne pathogens and the development of national guidelines on this subject, we appreciate the development of proxy measures for risk assessment. Ross et al¹ based their calculations on the following 4 determinants: A, the probability of HCV positivity in medical staff; B, the probability of percutaneous injuries; C, the probability of sharp object's recontact; and D, the rate of HCV transmission following exposure. If a surgeon is HCV RNA-positive, the risk of HCV transmission to a patient was calculated to range from 0.0062% to 0.057% resulting in 1 infection in 16 000 to 1 in 1750 invasive procedures, respectively. The worst-case calculation was based on B = 2.3%, C = . . . [Full Text of this Article]