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  Vol. 162 No. 1, January 14, 2002 TABLE OF CONTENTS
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The Intravenous Use of Oral Acetylcysteine (Mucomyst) for the Treatment of Acetaminophen Overdose

Arch Intern Med. 2002;162:96-97.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Acetaminophen remains one of the most common potentially lethal ingested substances encountered in clinical practice.1 Treatment for acetaminophen poisoning in the United States has remained the same during the past few years, while treatment outside the United States has taken a different path. The clinical standard between the United States and other countries differs in regard to intravenous acetylcysteine. The oral acetylcysteine protocol used in the United States has been effective. However, there are certain conditions, such as severe vomiting, for which oral administration is not possible. Great Britain and Canada use an intravenous formulation of acetylcysteine that has been available for many years.2 Intravenous acetylcysteine is not approved by the Food and Drug Administration (FDA), but certain instances have arisen during which the use of oral acetylcysteine intravenously has been potentially lifesaving.

Report of a Case

An 18-year-old woman presented to the emergency department 4 hours after ingesting 50 extra-strength acetaminophen tablets (25 . . . [Full Text of this Article]


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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

N-Acetylcysteine Decreases Angiotensin II Receptor Binding in Vascular Smooth Muscle Cells
Ullian et al.
J. Am. Soc. Nephrol. 2005;16:2346-2353.
ABSTRACT | FULL TEXT  

Adult Toxicology in Critical Care: Part II: Specific Poisonings
Mokhlesi et al.
Chest 2003;123:897-922.
FULL TEXT  





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