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A Case Report and Review of Treatment Options

Gregory S. Ahearn, MD; Denis Hadjiliadis, MD; Joseph A. Govert, MD; Victor F. Tapson, MD

Arch Intern Med. 2002;162:1221-1227.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Thromboembolic disease is an important cause of morbidity and mortality during pregnancy.¹ Berg and colleagues² found that 11% of maternal deaths during pregnancy were related to pulmonary embolism (PE). Another study revealed that up to 40% of pregnant women with asymptomatic deep vein thrombosis (DVT) may also have concurrent PE.³ Women are at increased risk for DVT and PE during pregnancy for several reasons. Pregnancy is a thrombophilic state; fibrinogen levels are increased, and during the final trimester there is a decrease in fibrinolytic activity. In addition, the gravid uterus causes compression and stasis in the lower extremities and pelvic veins favoring thrombosis.³ Finally, women with a history of thrombotic complications during pregnancy have an increased prevalence of genetic mutations related to coagulation.⁴

Traditionally, thromboembolic disease during pregnancy has been treated with unfractionated⁵ and, more . . . [Full Text of this Article]

REPORT OF A CASE

EMBOLECTOMY

THROMBOLYTIC THERAPY

CATHETER-DIRECTED THROMBOLYTIC THERAPY

VENA CAVA FILTERS

CONCLUSIONS

From the Department of Medicine, Division of Pulmonary and Critical Care, Duke University Medical Center, Durham, NC.

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