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Hepatobiliary Alterations in Patients With Inflammatory Bowel Disease
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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We read the very interesting article by Fraquelli et al1
that appeared in the October 8, 2001, issue of the ARCHIVES in which the authors
reported a significantly higher frequency of gallstone disease in patients
with Crohn disease (CD) than that reported in the general population. Moreover,
age, site of disease at diagnosis, and the history, number, and site of bowel
resections were independently associated with gallstone disease.
In this regard, we examined, in a GISC (Gruppo Italiano di Studio del
Colon-Retto) collaborative study,2 484 consecutive
patients with inflammatory bowel disease (IBD) with no previous known liver
disease or viral-related hepatic damage and healthy controls pair matched
for sex and age (±5 years). Our series included 317 patients with ulcerative
colitis (UC) (189 males and 128 females; mean ± SD age, 41 ±
15 years; range, 11-78 years) and 167 with CD (88 males and 79 females; mean
± SD . . . [Full Text of this Article]
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