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Both the article by Grandi et al¹ showing that patients with IOH, or white-coat hypertension, had increased left ventricular mass and the accompanying editorial² recommending that patients with IOH should be given medication misrepresent the relationship between ABPM and echocardiographic assessment of left ventricular mass as found in many larger and better-designed studies. Furthermore, Dr Moser's extrapolation of the results of this single study¹ to long-term outcomes avoids the central issue: which assessments of BP best predict future cardiovascular morbidity and mortality and provide some basis for selecting treatment? Abundant epidemiologic surveys indicate that the long-term average BP, corrected for regression dilution, is the best predictor of risk.³ Short-term measurement of office BPs, especially when they are near cutoff points for normal, all too often result in a false-positive diagnosis of hypertension.⁴ Hence, supplemental BP readings, taken at home with reliable methods or with ABPM, provide more precise averages. These . . . [Full Text of this Article]