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Antiphospholipid Antibodies
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Thomas makes several erroneous statements in respect to antiphospholipid
antibody (APLA) syndromes in his review entitled "Hypercoagulability Syndromes."1 Since readers may use these recommendations for
patient management decisions, we believe that these statements need to be
corrected.
1. Thomas states that the incidence of APLA syndrome is 28%. No data
exist to support this statement. The actual incidence of the syndrome in patients
with venous thromboembolism, as defined by the Sapporo criteria, is not known.2 Several studies have looked at the incidence of
APLAs in patients with venous thromboembolism, with results ranging from 5.2%
to 21%.3-4 These studies
used only a single measurement for APLAs. Since some APLAs are transient and
the APLA syndrome is defined by repeatedly positive APLA test results, the
incidence of the APLA syndrome is likely lower than 5.2% to 21%.
2. It is not correct that " . . . in 65% of patients [with . . . [Full Text of this Article]
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