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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Thomas¹ has proposed in the November 12, 2001, issue of the ARCHIVES a practical review of hypercoagulability syndromes. We would like to comment on several points. Indications of thrombophilia screening remain a matter of debate and we regret that this point was not discussed in the article. Limiting this debate to its financial aspect, as it could be interpreted from Table 2, which gives the cost of different assays, is not correct in our opinion. For instance, detecting an increase of factor VIII ($90) today has no recognized therapeutic implications, whereas elevated homocysteine concentration ($324) can lead to safe, inexpensive, and probably effective vitamin supplementation. Which screening to use and for which patients is a very difficult problem that has been discussed elsewhere and that must not be overlooked.² In the summary, Thomas stated that hypercoagulability syndrome can be "correctly diagnosed" in approximately 80% to 90% of patients. This appears . . . [Full Text of this Article]