
Biosurgical Debridement Facilitates Healing of Chronic Skin Ulcers
Arch Intern Med. 2002;162:1906-1907.
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Wound infection and retention of collagenous debris often impede the
healing of chronic skin ulcers. We cultivated the fly species Lucilia sericata and used live larvae to debride the ulcer ground of
necrotic tissue in 6 cases of refractory skin ulcers. Biosurgery by larvae
is a feasible and effective approach for cleansing debris and microbial infestation.
Chronic skin ulcers represent a major problem in health care. Before
surgical intervention or skin grafting, the ulcers have to be clean in terms
both of collagenous debris and of bacterial overgrowth. An interesting alternative
to the often ineffective use of fibrinolytic and collagenolytic enzyme preparations1-3 is the application
of living fly maggots.4 Larvae of certain
fly species digest all necrotic material, but never damage living tissue.5 This application has been termed biosurgery. We describe a case series of 6 patients in whom biosurgery
either served as an essential preparation for skin grafting . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Nigam et al.
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ABSTRACT
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