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Pulmonary Renal Syndrome and Thrombotic Thrombocytopenic Purpura in a Patient With Giant Cavernous Hemangioma of the Leg
Arch Intern Med. 2002;162:221-222.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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The microangiopathic hemolytic disorders cover a wide spectrum of clinical
disorders and have a variety of underlying and triggering causes. Early diagnosis
and treatment are essential to minimize organ damage and improve prognosis.
Report of a Case
A 60-year-old man with giant congenital cavernous hemangioma of the
leg (Figure 1, A) was admitted for
recurrent gastrointestinal bleeding for 1 year. On admission his platelet
count and coagulation profile were normal. Celiac angiogram, red blood cell
scintiscan (Figure 1, B) and laparotomy
led to the uneventful resection of 3 bleeding ileal segments. One week after
the third surgery, he developed acute pallor, jaundice, fever, and oliguria.
Investigations showed a low hemoglobin level (6.2 g/dL) and platelet count
(12 x 103/µL), absent haptoglobin, a grossly elevated
lactate dehydrogenase level (3560 U/L; normal, 197-401 U/L), and an elevated
creatinine level (9.6 mg/dL [850 µmol/L]; normal, 0.9-1.4 mg/dL [76-128
µmol/L]), with a normal . . . [Full Text of this Article] Comment
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