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We read with interest the recent review by Felson and Anderson¹ titled "Hyaluronate Sodium Injections for Osteoarthritis: Hope, Hype, and Hard Truths," published in the February issue of the ARCHIVES. In contrast to the review, we find that intra-articular hyaluronan (HA) is an effective therapy for reducing pain associated with osteoarthritis (OA) of the knee for many of our patients. Hyaluronan is a safe and efficacious treatment modality that has been confirmed in numerous controlled clinical studies. We believe that many of the so-called hard truth(s) in this review are misleading.

The review by Felson and Anderson failed to cite or mention the numerous favorable review articles that more comprehensively reviewed the clinical evidence,^2-8 yet selectively cited the recently published most negative review.⁹ Similarly, the authors failed to acknowledge that the American College of Rheumatology Subcommittee on Osteoarthritis Guideline's recently published "Recommendations for the Medical Management of Osteoarthritis of the . . . [Full Text of this Article]

RELATED ARTICLE

Hyaluronate Sodium Injections for Osteoarthritis: Hope, Hype, and Hard Truths
David T. Felson and Jennifer J. Anderson
Arch Intern Med. 2002;162(3):245-247.
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