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  Vol. 162 No. 4, February 25, 2002 TABLE OF CONTENTS
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Increased Blood Pressure Variability May Be Associated With Cognitive Decline in Hypertensive Elderly Subjects With No Dementia

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

As Birkenhäger and colleagues1 suggested in their article, the decrement of blood pressure (BP) occurring in patients with hypertension in the phases shortly before dementia may be related to a central dysregulation of prefrontal autonomic centers. To contribute to this topic, we have studied the relationship between cognitive function and BP variability, which is known to reflect an altered baroreflex sensitivity.2 We evaluated 34 elderly patients consecutively admitted to our hospital with no dementia (normal or mild cognitive impairment according to the Petersen criteria).3 All patients underwent a neuropsychological assessment to evaluate cognitive functions (Table 1) and a noninvasive, 24-hour BP monitoring (using the Intermed Takeda TM-2430; A & D Instruments Ltd, Abingdon, Oxford, England) to determine the circadian BP profile.


 
Table appears in full text version.
Clinical Characteristics of 34 Patients With Absent or Mild Cognitive Impairment Stratified by Mini-Mental State Examination (MMSE) Scores Adjusted for Age and Sex*


The daytime BP measurements . . . [Full Text of this Article]


RELATED ARTICLE

Blood Pressure, Cognitive Functions, and Prevention of Dementias in Older Patients With Hypertension
Willem H. Birkenhäger, Françoise Forette, Marie-Laure Seux, Ji-Guang Wang, and Jan A. Staessen
Arch Intern Med. 2001;161(2):152-156.
ABSTRACT | FULL TEXT  


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Stress-induced blood pressure reactivity and cognitive function
Waldstein and Katzel
Neurology 2005;64:1746-1749.
ABSTRACT | FULL TEXT  





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