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Let's Strip the King: Eligibility Not Safety Is the Problem of Anticoagulation for Stroke Prevention in Elderly Patients With Atrial Fibrillation
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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In their retrospective follow-up study of all patients attending a hospital
anticoagulant clinic for atrial fibrillation, Copland and colleagues1 found that the elderly population has both good
anticoagulant control and a low incidence of hemorrhage while receiving warfarin
therapy. Although interesting, from our point of view, these data cannot support
the authors' general conclusion in favor of anticoagulant use. In fact, in
the "Patients, Materials, and Methods" section, the authors note that prosthetic
heart valve replacement was the only exclusion criterion, implicitly admitting
the possibility of "a selection bias at the level of referral to the clinic."
We would like to comment on this bias with our recent data,2-4 reporting that
global cognitive, functional, and comorbidity status strongly influence the
assignment to aspirin or anticoagulant therapy in the elderly population both
in the hospital and in the community. In particular, we also found that among
general practitioners in the community, . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Trends in the prevalence of diagnosed atrial fibrillation, its treatment with anticoagulation and predictors of such treatment in UK primary care
DeWilde et al.
Heart 2006;92:1064-1070.
ABSTRACT
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