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In reply. We share with Drs Satoh and Sekizawa an interest in the important impact of comorbid illnesses on the management of respiratory diseases. They bring up the importance of comorbid coronary artery disease (CAD) and arrhythmia, which may increase the risk of hospitalization for patients with asthma. In our article,¹ we focused on certain prespecified comorbid conditions. However, the survey we administered also included information about self-reported angina and history of prior myocardial infarction. We did not obtain information about arrhythmia. In our study, there was a strong, positive association between older age and a history of angina and/or myocardial infarction (18-34 years, 1.0%; 25-44 years, 2.0%; 45-54 years, 5.2%; 55-64 years, 11.4%; 65 years, 17.5%; P<.001). In addition, hospitalization for asthma was more likely in patients who had a history of CAD compared with those who did not (11.8% vs 4.5%;P<.001). In our article, the . . . [Full Text of this Article]