This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Related letters  • Similar articles in this journal  Topic Collections  • Hematology/ Hematologic Malignancies  • Hematology, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Intern Med. 2003;163:1371-1373.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Eosinophils were first described in 1879 by Paul Ehrlich, based on their staining behavior. Eosinophils are a subpopulation of leukocytes, originating in the bone marrow from a CD34⁺ precursor. They circulate in peripheral blood, where they represent 2% to 3% of total white cells, and have a half-life of approximately 8 to 18 hours. Nevertheless, once recruited in peripheral tissues by specific cytokines, eosinophils can survive for days or weeks as resident cells. Eosinophils possess a powerful enzymatic machinery (eosinophil-derived neurotoxin, eosinophil cationic protein, and major basic protein) not shared with other types of granulocytes.¹

Since their discovery, eosinophils have raised a remarkable interest because their increase in peripheral blood was found to be associated with specific groups of diseases, such as allergic disorders and parasitic infections. For decades they were considered as bystander cells in such diseases; presently, thanks to the new diagnostic and laboratory techniques, its proinflammatory role . . . [Full Text of this Article]

Methods


Results

Comment


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED LETTERS

Iatrogenic Eosinophilia
Takeharu Koga and Hisamichi Aizawa
Arch Intern Med. 2004;164(1):106.
EXTRACT | FULL TEXT  

Iatrogenic Eosinophilia—Reply
Giovanni Passalacqua and Carlo Lombardi
Arch Intern Med. 2004;164(1):106.
EXTRACT | FULL TEXT  

Gastrointestinal Conditions With Eosinophilia
Ranjit Sinharay
Arch Intern Med. 2004;164(7):805-806.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

How the public is being misled about complementary/alternative medicine
Ernst
JRSM 2008;101:528-530.
FULL TEXT  

Atypical Presentation of Eosinophilic Endomyocardial Disease
Blauwet et al.
Mayo Clin Proc. 2005;80:1078-1084.
ABSTRACT  

The potential impact of the use of homeopathic and herbal remedies on monitoring the safety of prescription products
Woodward
Hum Exp Toxicol 2005;24:219-233.
ABSTRACT  

Perindopril and pulmonary eosinophilic syndrome
Rochford et al.
JRSM 2005;98:163-165.
FULL TEXT  

Natural Health Product Interactions with Medication
Boullata
Nutr Clin Pract 2005;20:33-51.
ABSTRACT | FULL TEXT  

Gastrointestinal Conditions With Eosinophilia
Sinharay
Arch Intern Med 2004;164:805-806.
FULL TEXT  

Iatrogenic Eosinophilia
Koga and Aizawa
Arch Intern Med 2004;164:106-106.
FULL TEXT  

Iatrogenic Eosinophilia--Reply
Passalacqua and Lombardi
Arch Intern Med 2004;164:106-106.
FULL TEXT  

Herbal medicines
Pirmohamed
Postgrad. Med. J. 2003;79:489-489.
FULL TEXT