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Nonspecific Guidelines Lead to Inappropriate Fluoroquinolone Use
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Although a small study, the article by Lautenbach et al1 underscores the alarming prevalence of inappropriate fluoroquinolone use in a sample of emergency departments. Particularly in the setting of community-acquired pneumonia (CAP), the widespread use of fluoroquinolones has led to emergence of not only resistant pneumococci, but also a host of gram-negative organisms that often have nothing to do with the cause of a patient's pneumonia.2 One of the problems of influencing practitioners treating CAP to limit the use of fluoroquinolones to those deemed appropriate for such therapy1 is the lack specific recommendations for the treatment of CAP by guidelines published by the American Thoracic Society and Infectious Diseases Society of America (IDSA). In outpatient CAP, the IDSA recommends doxycycline, a macrolide, or a fluoroquinolone in no specific order of preference.3 In stable, hospitalized patients, the American Thoracic Society recommends an intravenous -lactam plus an intravenous or oral macrolide, or . . . [Full Text of this Article]
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Nonspecific Guidelines Lead to Inappropriate Fluoroquinolone UseReply
Ebbing Lautenbach, Lori A. Larosa, Nishaminy Kasbekar, Helen P. Peng, Richard J. Maniglia, and Neil O. Fishman
Arch Intern Med. 2003;163(13):1618.
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