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The aim of our study was to examine the "real-world" characteristics of serum creatinine as a screening test for chronic kidney disease (CKD) in elderly patients. We demonstrated that a serum creatinine level of 1.7 mg/dL (150 µmol/L) had very poor sensitivity (12.6%) for the detection of CKD. Therefore, we recommend that estimated GFR, and not serum creatinine level, be used for the screening of CKD. While we used the C-G equation to calculate GFR in our study, we do not advocate its use over any other valid method to estimate GFR. The NKF endorses the use of both the C-G equation and the MDRD Study equation as acceptable alternatives to estimate the GFR.¹ We selected the C-G equation because it has been extensively validated in a variety of populations, is simple to use, and can be readily applied at the bedside with a basic calculator.^1-2 As Bernheim . . . [Full Text of this Article]

Peter J. Swedko, MD; Heather D. Clark, MD; Ayub Akbari, MD
Ottawa, Ontario

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