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Associations Between Body Mass Index and Risks in Elderly Patients With a First-Ever Acute Ischemic Stroke—Reply
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In reply
Milionis and colleagues' interesting data nicely complement our study results,1 and emphasize that excess weight is an important modifiable risk factor for stroke. In their study, a body mass index (BMI) of 27 or greater was associated with a 24% increase in the risk of nonembolic ischemic stroke in the elderly compared with a BMI of less than 27.
When we used a BMI cut point of 27 or greater in our cohort, the effect of excess weight on ischemic stroke tended to be greater in younger than in older people. Among men who were younger than 70 years at baseline in 1982, for BMIs of 27 or greater, the age-adjusted relative risk was 1.57 (95% confidence interval, 1.28-1.92) compared with participants with BMIs less than 27. Interestingly, when we restricted our analyses to participants 70 years and older at baseline and used the BMI categorization of Milionis . . . [Full Text of this Article]
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