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	Since this article does not have an abstract, we have provided the first 123 words of the full text and any section headings.

A detailed analysis on the causes of peripheral blood eosinophilia by Lombardi and Passalacqua¹ was greatly appreciated in terms of providing clinicians with directions in evaluating this common clinical problem. In addition to the disorders mentioned by the authors, we would like to raise the awareness of iatrogenic eosinophilia (most cases of which are induced by drugs and less frequently by radiocontrast materials²) as a common cause of peripheral blood eosinophilia, especially in developed countries. Clinical presentations vary from simple laboratory abnormalities to lethal episodes. Avoidance of the culprit agent is essential when treatment is needed. It may complicate underlying disorders associated with eosinophilia. Considering these possibilities, clinicians should always keep iatrogenic eosinophilia in mind when evaluating patients with peripheral blood eosinophilia.

Takeharu Koga, MD; Hisamichi Aizawa, MD
Kurume, Japan

1. Lombardi C, Passalacqua G. Eosinophilia and diseases: clinical revision of 1862 cases. Arch Intern Med. 2003;163:1371-1373. FREE FULL TEXT 2. Plavsic BM, Newman AC, Reuther WL, Terry JA, Drnovsek VH. Peripheral blood eosinophilia associated with gastrointestinal administration of iodinated contrast media. AJR Am J Roentgenol. 2003;180:751-753. FREE FULL TEXT

Arch Intern Med. 2004;164:106.

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