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Venous Thrombosis in Long-Haul Travelers
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Schwarz et al1 reported that the incidence of venous thrombosis among long-haul flight travelers was 2.8% compared with 1.0% in controls. However, 20 of 27 events in travelers and 10 of 12 events in controls were isolated calf muscle vein thromboses (ICMVT). The authors conclude that ICMVT may be used as a surrogate marker of air travel–associated deep venous thrombosis (DVT) and that while "the natural history of ICMVT is not known . . . ICMVT has been suggested to be the first step toward deep venous thrombosis."
Our group recently performed a study to elucidate the natural history of untreated ICMVT, diagnosed by compression ultrasonography in patients who had been referred because of clinically suspected DVT.2 After diagnosis, patients underwent serial ultrasonography on days 5, 9, 14, 30, and 90, or until extension or complete resolution of the thrombus was demonstrated. Patients whose thrombi extended into the deep calf . . . [Full Text of this Article]
Susan R. Kahn, MD, FRCPC, MSc
Correspondence: Dr Khan, Center for Clinical Epidemiology & Community Studies, Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste Catherine Rd, Room A-127, Montreal, Quebec, Canada H3T 1E2 (susan.kahn@mcgill.ca).
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