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In-Hospital Mortality and Long-term Use of Inhaled Corticosteroids
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I read with great interest the cross-sectional study data reported by Patil et al1 about generalizable estimates, admission characteristics, and risk factors for in-hospital mortality in patients admitted for acute exacerbation of chronic obstructive pulmonary disease (COPD). The authors comment that age, sex, median income, comorbid illnesses, nonroutine admissions, and insurance status have a bearing on mortality during hospitalization. The relationship between long-term use of inhaled corticosteroids (ICSs) and systemic corticosteroids on in-hospital mortality was not studied.
In a population-based cohort study using administrative databases in Ontario, Canada (n = 22 620), to determine the association between ICS therapy and the combined risk of repeated hospitalization and all-cause mortality in elderly patients with COPD, patients who received ICS therapy after discharge (within 90 days) had 24% fewer repeated hospitalizations for COPD (95% confidence interval , 22%-35%) and were 29% less likely to experience mortality (95% confidence interval, 22%-35%) during 1 year . . . [Full Text of this Article]
Sujeeth R. Punnam, MD
Nacogdoches, Tex
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