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Ulcerative colitis and Crohn disease are related chronic inflammatory bowel diseases (IBDs), with a combined incidence of 11 to 19 per 100 000 persons in the United States.¹ Although the cause of IBDs is unknown, they are classified as autoimmune diseases.² Patients with IBD show antibodies against different antigens, although it is still unclear if they represent an epiphenomenon of chronic inflammation or represent the cause of IBD.³

Among patients with IBD, the prevalence of infertility is higher than in healthy subjects.⁴ It has been suggested that anatomical alterations due to chronic abdominal inflammation leading to tubal obstruction in female patients and spermatogenesis impairment due to therapeutic agents for IBD in male patients could be the causes of infertility.⁵ We evaluated 10 patients (4 women and 6 men; age range, 31-39 years) referred to our center for infertility, who had a clinical history of IBD. The results from all diagnostic procedures . . . [Full Text of this Article]

AUTHOR INFORMATION
Marco Rossato, MD, PhD; Carlo Foresta, MD

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