This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Thrombolysis  • Venous Thromboembolism  • Cardiovascular System  • Alert me on articles by topic  Social Bookmarking   What's this?

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We were pleased to see so much attention given to air travel–related venous thrombo-embolism (VTE) in a recent issue of the ARCHIVES.^1-3 However, the accompanying editorial misquoted a misleading study.⁴ The editorial correctly notes that 2 randomized trials^5-6 have demonstrated that compression stockings markedly reduce the incidence of deep vein thrombosis (DVT) during long-haul airplane flights. However, the editorial also cites the LONFLIT3 study,⁷ stating that these investigators randomized 200 high-risk passengers to low-molecular-weight heparin (LMWH) vs placebo and that the incidence of DVT was 4.8% in the control group vs 0% in the placebo group (P<.002). In fact, the LONFLIT3 study was underpowered and failed to demonstrate a statistically significant difference between the LMWH group and the placebo group in DVT incidence. The study enrolled 300 patients to 3 arms (100 patients each): an LMWH arm, a placebo arm, and a low-dose aspirin arm. A . . . [Full Text of this Article]

AUTHOR INFORMATION
Daniel J. Brotman, MD; Amir K. Jaffer, MD

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

RELATED ARTICLES

Economy Class Syndrome: Too Much Flying or Too Much Sitting?
James E. Dalen
Arch Intern Med. 2003;163(22):2674-2676.
EXTRACT | FULL TEXT  

Venous Thrombosis After Long-haul Flights
Thomas Schwarz, Gabriele Siegert, Wolfram Oettler, Kai Halbritter, Jan Beyer, Roswitha Frommhold, Siegmund Gehrisch, Florian Lenz, Eberhard Kuhlisch, Hans-Egbert Schroeder, and Sebastian M. Schellong
Arch Intern Med. 2003;163(22):2759-2764.
ABSTRACT | FULL TEXT  

Incidence of Air Travel–Related Pulmonary Embolism at the Madrid-Barajas Airport
Esteban Pérez-Rodríguez, David Jiménez, Gema Díaz, Ivan Pérez-Walton, Manuel Luque, Carmen Guillén, Eva Mañas, and Roger D. Yusen
Arch Intern Med. 2003;163(22):2766-2770.
ABSTRACT | FULL TEXT  

Risk of Venous Thromboembolism After Air Travel: Interaction With Thrombophilia and Oral Contraceptives
Ida Martinelli, Emanuela Taioli, Tullia Battaglioli, Gian Marco Podda, Serena Maria Passamonti, Paola Pedotti, and Pier Mannuccio Mannucci
Arch Intern Med. 2003;163(22):2771-2774.
ABSTRACT | FULL TEXT