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Clarification of Patient Population in Sinusitis Article
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I was intrigued by the abstract of the article by Bucher et al1 about the failure of antibiotics over placebo in acute rhinosinusitis. As I read the article I became confused over the patient population the authors were describing. I assume these were patients who started with classic signs of upper respiratory tract infection (URTI) such as rhinorrhea, sore throat, and perhaps lymphadenopathy and cough, but whose prominent feature was the presence of acute rhinosinusitis. It is implied that these patients were afebrile, although this information is not included. Nor was there any information about time of onset of the URTI to development of the sinusitis or other symptoms such as sore throat, nasal congestion, or cough. When I first looked at the data, I thought the authors were referring to patients who came in with no signs of URTI other than the sinusitis, and I'm still unsure which of . . . [Full Text of this Article]
Melvyn G. Weinberg, MD
Tucson, Ariz
RELATED ARTICLE
Effect of Amoxicillin-Clavulanate in Clinically Diagnosed Acute Rhinosinusitis: A Placebo-Controlled, Double-blind, Randomized Trial in General Practice
Heiner C. Bucher, Peter Tschudi, James Young, Pierre Périat, Antje Welge-Lüssen, Hansjörg Züst, and Christian Schindler
Arch Intern Med. 2003;163(15):1793-1798.
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