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Comments on a Comprehensive Strategy to Prevent Methicillin-Resistant Staphylococcus aureus Infections
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Tomic et al1 describe the effectiveness of a rigorous infection control program to prevent nosocomial spread of methicillin-resistant Staphylococcus aureus (MRSA) in a hospital in Slovenia. After 1 year of observations, the promotion of hand hygiene, active surveillance cultures at admission to identify MRSA carriers, strict application of barrier precautions for patients with MRSA, eradication of MRSA carriage, and continuous education of health care workers on appropriate hygiene procedures was implemented, and the incidence of MRSA was measured during 4 years.
According to the authors, this would be a prospective cohort study. We believe that such a set of rigorous procedures would better fit the quasi-experimentation design with historical controls. Different from an experimental study, it is prone to bias due to co-intervention, such as a change in the profile of patients with imported and acquired infection. The authors pointed out that the annual incidence of detected MRSA carriers increased . . . [Full Text of this Article]
AUTHOR INFORMATION
Cícero Dias, MSc, PharmD;
Sandra Costa Fuchs, MD, PhD;
Rejane Oravec, MD;
Fernanda Freitag, MD;
Luciele Shifelbain, MD
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