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A Prediction Model for Isolating Inpatients With Suspected Pulmonary Tuberculosis—Reply
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In reply
As Tattevin and Bouvet point out, the clinical and radiological presentation of TB among HIV-infected patients may be atypical, and thus the prediction rule may perform differently according to the prevalence of having HIV-positive individuals among patients suspected of TB. However, the model is composed of predictors, such as upper lobe infiltrate on chest radiograph or a positive tuberculin skin test result, that are usually considered to be "typical" of TB among HIV-negative patients. Thus, our finding that the rule had a high sensitivity in a population with a high prevalence of HIV-infected patients further supports the generalizability of the model, regardless of the patient’s HIV status.
We agree with Lee and Chen that failing to isolate patients with active TB can result in nosocomial transmission of TB and originate considerable costs. To protect patients’ confidentially right, we collected minimal information for those individuals who did not participate . . . [Full Text of this Article]
AUTHOR INFORMATION
Juan P. Wisnivesky, MD, MPH;
Thomas G. McGinn, MD, MPH
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