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Hoyt raises the question of the serum 25-hydroxyvitamin D levels in the patients with osteoporosis and celiac disease compared with those with osteoporosis but without celiac disease. Among those 9 patients with both osteoporosis and celiac disease, 5 had 25-hydroxyvitamin D levels below 15 ng/mL (<37.4 nmol/L) with a mean level of 16.9 ± 6.2 ng/mL (42.2 ± 15.5 nmol/L), whereas among those 36 patients with osteoporosis but without celiac disease, 5 had levels below 15 ng/mL (<37.4 nmol/L) and the mean was 26.6 ± 13 ng/mL (66.4 ± 32.4 nmol/L). All 9 patients with celiac disease and osteoporosis were receiving calcium, but only 1 was receiving vitamin D.

As we discussed in the article, we found that most celiac patients with osteoporosis had chemically evident secondary hyperparathyroidism with 25-hydroxyvitamin D deficiency, consistent with the notion that vitamin D malabsorption or poor intake is common in this population.¹

AUTHOR INFORMATION
Correspondence: Dr Stenson, Division of Gastroenterology, Washington . . . [Full Text of this Article]

William F. Stenson, MD

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